Lion's Mane mushrooms in a basket

Can You Combine Different Types of Mushrooms?

Welcome to the world of adaptogen mushrooms! Some are all about your brain function. Others are here for your nervous system. Most boost your immune system. All of them are about restoration and regeneration.

Traditional Chinese Medicine (TCM) and Eastern medicine have incorporated medicinal mushrooms for centuries. Mushroom supplements have grown in popularity over the last ten years thanks to modern research's willingness to include mushrooms in studies. The clinical evidence gained in these confirms the historical reverence of functional mushrooms.

Editor's note: Adaptogen mushrooms are also referred to as nootropics. Nootropics are substances or herbs that enhance mental health. A nootropic stack can include more than just mushrooms.

Can You "Stack" Mushrooms?

Different mushrooms target different areas of the body and mind. One of the most common questions is, "Can you take multiple mushroom supplements at once?" You can and should. When combined or "stacked," mushrooms work collaboratively on your body and mind. Each mushroom brings its unique flair to each combination.

The right mushroom stack for you is about what you seek.

  • For an immunity boost, combine Turkey Tail and Reishi.
  • To maintain productive focus, combine Cordyceps and Lion's Mane.
  • To achieve balanced calm, combine Chaga and Reishi.
  • For an energy boost, combine Chaga and Cordyceps.
  • To increase cognitive function, combine Lion's Mane and Reishi.

Build Your Mushroom Stack

Pick everything you want support with. We'll show which mushrooms are studied for each goal and when to take them.

What do you want support with? Pick all that apply.

Pick at least one goal to see your stack.

Your mushroom stack

Lion's Mane (Hericium erinaceus)

The mushroom most studied for focus, memory, and cognitive function. Older adults who took it daily for 16 weeks scored better on a cognitive test than a placebo group.

Morning, often in coffee

Lion's Mane Capsules · Powder · Tincture

Cordyceps (Cordyceps militaris)

Studied for energy and endurance. In a small trial, active adults saw endurance changes after 3 weeks of a daily Cordyceps blend.

Morning, or 30 to 60 minutes before a workout

We don't sell Cordyceps on its own. It's one of the seven in Sacred 7.

Reishi (Ganoderma lucidum)

Studied for calm, stress, sleep, and immune support. The classic evening mushroom.

Evening

Reishi Tincture: two droppers in a warm mug of tea.

Turkey Tail (Trametes versicolor)

Studied for immune and gut health, mainly through its PSK and PSP polysaccharides. Benefits build with daily use.

Any time, with food

Find it in Sacred 7.

Shiitake and Maitake

Both studied for immune support, through lentinan in Shiitake and D-fraction beta-glucans in Maitake.

Any time, with a meal

Both are in Sacred 7.

Chaga (Inonotus obliquus)

Studied for antioxidant support, from its polyphenols, melanin, and beta-glucans. Wild-harvested from Alaskan birch.

Morning or afternoon

Chaga Tincture, or in Sacred 7.

Or Take Your Whole Stack in One Teaspoon

Every mushroom above is in Sacred 7: 143mg each of Reishi, Lion's Mane, Cordyceps militaris, Chaga, Turkey Tail, Shiitake, and Maitake. That's 1,000mg of 100% fruiting body extract, hot water extracted and USDA Certified Organic. Three capsules equal one teaspoon.

Shop Sacred 7 Powder →Shop Sacred 7 Capsules →

Worth checking with your provider

Reishi may add to the effect of blood thinners and blood pressure medications.

Chaga is high in oxalates, which matters if you've had kidney stones, and may affect blood sugar and clotting.

Maitake is studied for blood sugar, so check first if you take diabetes medication.

Sacred 7 includes Reishi, Chaga, and Maitake, so those notes apply to it too. Check first if you're pregnant or breastfeeding, take immune-suppressing drugs, or have surgery coming up.

When to take each one, and what the first weeks look like: When Is the Best Time to Take Mushroom Supplements?

As you can see, the combinations are endless! A blended supplement strategy is a go-to way to consume functional mushrooms. That's part of the reason we launched our Sacred 7 Mushroom Extract Powder.

The Sacred 7 Stack

Our mushroom powder is an equal blend of seven real mushrooms: Chaga, Cordyceps, Lion's Mane, Maitake, Reishi, Shiitake, and Turkey Tail. We recommend a 1000mg/day dosage, from which you'd get 143mg of each mushroom.

Three popular supplement combinations are Reishi and Chaga, Lion's Mane and Reishi, and Lion's Mane and Cordyceps. With Sacred 7, you're adding Turkey Tail for immunity, Maitake for energy, and Shiitake for nutrition to these powerful combinations.

We preserve the mushrooms' adaptogenic, longevity-promoting compounds because we use only whole organic fruiting bodies. They're also organic, non-GMO, vegan, gluten-free, paleo, and keto-friendly. You can buy our USDA Organic Sacred 7 Mushroom Extract Powder or Sacred 7 Capsules here on our site.

So, what does each type of mushroom in Sacred 7 offer?

Chaga Mushrooms

Chaga mushrooms grow on the bark of Birch trees in cold climates. Per studies in the National Library of Medicine, Chaga is a friend to the immune system and promotes immune function. Rich in antioxidants, Chaga also boosts immunity, fights inflammation, and lowers cholesterol. It may benefit skin tone and texture based on its triterpenes, betulinic acid, melanin, and other unique compounds.

Cordyceps Mushrooms

Cordyceps mushrooms are traditionally grown at high altitudes. Another "all-healer" variety, research shows that cordyceps improve energy, stamina, and libido by boosting ATP production. They also help regulate sleeping patterns, are cognition-enhancers, and aid with asthma, per studies in the National Library of Medicine. They are also known to carry beta-glucan polysaccharides, known for their immune system-based benefits.

Lion's Mane Mushrooms

A champion of nerve and brain health, Lion's Mane mushrooms contain triterpenes, hericenone, and erinacine. Both affect mental clarity, nerve growth factor, and immune support. Research studies found that it may protect against dementia and reduce mild anxiety symptoms. Studies also prove its gastroprotective properties, especially regarding ulcers, stomach cancers, IBS, and menstrual pain.

Maitake Mushrooms

Also known as hen-of-the-woods, maitake mushrooms is a popular culinary mushroom superfood in addition to being a part of the Sacred 7 blend. Maitake mushrooms also contain polysaccharides that can reduce bad cholesterol (LDL) without affecting good cholesterol (HDL) levels. A practical solution in diabetes management, maitake is also proven to lower blood sugar levels.

Reishi Mushrooms

Reishi is consistently used in dietary supplements and extract powders of medicinal mushrooms thanks to its health benefits and neuroprotective properties. Research links Reishi mushrooms to white blood cell production, which helps fight infection. In addition to immune function and cognitive performance, Reishi mushrooms support gut health. A 2017 study even found evidence that Reishi suppresses breast cancer cell growth.

Shiitake Mushrooms

A deliciously gourmet variety, Shiitake is one of the best mushrooms attributed to longevity through research. Like Reishi, it boosts white blood cell production and high-quality immune function. Similar to Maitake, Shiitake mushrooms support healthy blood glucose levels. It's also high in Vitamin D2, copper, and anti-inflammatory properties.

Turkey Tail Mushrooms

Turkey Tail mushrooms grow on stumps and decomposing wood and turn decay into medicinal gold. High in antioxidants and loaded with prebiotics to support gut health, Turkey Tail is even linked in various studies to helping specific cancer treatments. It's a powerful wellness tonic in traditional medicine.

We only understand a fraction of the power mushrooms holds. The network of mycelium connecting not just fungi but also trees and plants is a great natural system. We learn more daily, powered by work from mycologist pioneers like Dr. Andrew Weil and Paul Stamets. It's a great time to consider functional mushrooms in your routine.

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